KRT6A 抗体 (Middle Region)
Quick Overview for KRT6A 抗体 (Middle Region) (ABIN971015)
抗原
See all KRT6A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RGMQDLVEDF KNKYEDEINK RTAAENEFVT LKKDVDAAYM NKVELQAKAD
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预测反应
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
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产品特性
- This is a rabbit polyclonal antibody against KRT6A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 564 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KRT6A (Keratin 6A (KRT6A))
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别名
- KRT6A
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背景
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The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Alias Symbols: CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D
Protein Interaction Partner: TRIM54, KRT40, TFIP11, HGS, KRT38, SGTA, KRT31, KRT15, KRT13, KIFC3, GOLGA2, TRIM23, LGR4, EED, KDM1A, PAN2, Iqcb1, Nphp4, Cep290, Nphp1, Invs, UBC, ITGA4, ALB, UBASH3B, SHC1, GRB2, EPS15, CRK, AP2M1, CBL, CUL1, COPS5, CUL2, CUL5, CCDC85B, TCHP, CCDC53, K
Protein Size: 564 -
分子量
- 59 kDa
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基因ID
- 3853
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NCBI登录号
- NM_005554, NP_005545
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UniProt
- P02538
抗原
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