Deoxyguanosine Kinase 抗体 (C-Term)
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- 抗原 See all Deoxyguanosine Kinase (DGUOK) 抗体
- Deoxyguanosine Kinase (DGUOK)
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抗原表位
- C-Term
- 适用
- 人, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Deoxyguanosine Kinase antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EQLHGQHEAW LIHKTTKLHF EALMNIPVLV LDVNDDFSEE VTKQEDLMRE
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 85%
- 产品特性
- This is a rabbit polyclonal antibody against DGUOK. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGUOK
- Top Product
- Discover our top product DGUOK Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 277 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Deoxyguanosine Kinase (DGUOK)
- 别名
- DGUOK (DGUOK 产品)
- 背景
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In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
Alias Symbols: dGK
Protein Interaction Partner: UBC, PXN, LIG4, APP, DGUOK,
Protein Size: 277 - 分子量
- 28 kDa
- 基因ID
- 1716
- NCBI登录号
- NM_080916, NP_550438
- UniProt
- Q16854
- 途径
- Ribonucleoside Biosynthetic Process
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