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UNC13D 抗体 (C-Term)

UNC13D 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789769
发货至: 中国
  • 抗原 See all UNC13D 抗体
    UNC13D (Unc-13 Homolog D (UNC13D))
    抗原表位
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马
    宿主
    • 20
    • 3
    • 2
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 21
    • 2
    • 1
    • 1
    This UNC13D antibody is un-conjugated
    应用范围
    • 20
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    序列
    SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
    预测反应
    Cow: 92%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against UNC13D. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human UNC13D
    Top Product
    Discover our top product UNC13D Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    UNC13D (Unc-13 Homolog D (UNC13D))
    别名
    UNC13D (UNC13D 产品)
    别名
    FHL3 antibody, HLH3 antibody, HPLH3 antibody, Munc13-4 antibody, UNC13D antibody, 2610108D09Rik antibody, Jinx antibody, mFLJ00067 antibody, Unc13h4 antibody, BIGH3 antibody, CDB1 antibody, CDG2 antibody, CDGG1 antibody, CSD antibody, CSD1 antibody, CSD2 antibody, CSD3 antibody, EBMD antibody, LCD1 antibody, unc-13 homolog D antibody, unc-13 homolog D (C. elegans) antibody, transforming growth factor beta induced antibody, UNC13D antibody, Unc13d antibody, TGFBI antibody, unc13d antibody, un13d antibody
    背景
    This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
    Alias Symbols: FHL3, HLH3, HPLH3, Munc13-4
    Protein Interaction Partner: UBC, CUL5, VPS37B, XRN2, LMNA, RAB27B, RAB27A,
    Protein Size: 1090
    分子量
    119 kDa
    基因ID
    201294
    NCBI登录号
    NM_199242, NP_954712
    UniProt
    Q70J99
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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