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UNC13D 抗体 (C-Term)

UNC13D 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789769
发货至: 中国
  • 抗原 See all UNC13D 抗体
    UNC13D (Unc-13 Homolog D (UNC13D))
    抗原表位
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马
    宿主
    • 19
    • 3
    • 2
    克隆类型
    • 22
    • 2
    多克隆
    标记
    • 20
    • 2
    • 1
    • 1
    This UNC13D antibody is un-conjugated
    应用范围
    • 19
    • 11
    • 7
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    序列
    SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
    预测反应
    Cow: 92%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against UNC13D. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human UNC13D
    Top Product
    Discover our top product UNC13D Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    UNC13D (Unc-13 Homolog D (UNC13D))
    别名
    UNC13D (UNC13D 产品)
    背景
    This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
    Alias Symbols: FHL3, HLH3, HPLH3, Munc13-4
    Protein Interaction Partner: UBC, CUL5, VPS37B, XRN2, LMNA, RAB27B, RAB27A,
    Protein Size: 1090
    分子量
    119 kDa
    基因ID
    201294
    NCBI登录号
    NM_199242, NP_954712
    UniProt
    Q70J99
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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