UNC13D 抗体 (C-Term)
Quick Overview for UNC13D 抗体 (C-Term) (ABIN2789769)
抗原
See all UNC13D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
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预测反应
- Cow: 92%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against UNC13D. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human UNC13D
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anti-Unc-13 Homolog D (UNC13D) (AA 2-100) antibody
UNC13D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Unc-13 Homolog D (UNC13D) (Internal Region) antibodyVerified UNC13D 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 7-172) antibodyUNC13D 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyVerified UNC13D 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) antibodyUNC13D 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 891-1090) antibodyUNC13D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UNC13D (Unc-13 Homolog D (UNC13D))
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别名
- UNC13D
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背景
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This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Alias Symbols: FHL3, HLH3, HPLH3, Munc13-4
Protein Interaction Partner: UBC, CUL5, VPS37B, XRN2, LMNA, RAB27B, RAB27A,
Protein Size: 1090 -
分子量
- 119 kDa
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基因ID
- 201294
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NCBI登录号
- NM_199242, NP_954712
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UniProt
- Q70J99
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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