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DUSP4 抗体 (C-Term)

DUSP4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789728
发货至: 中国
  • 抗原 See all DUSP4 抗体
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    抗原表位
    • 16
    • 8
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 51
    • 34
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig
    宿主
    • 47
    • 4
    克隆类型
    • 47
    • 4
    多克隆
    标记
    • 24
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP4 antibody is un-conjugated
    应用范围
    • 44
    • 25
    • 20
    • 14
    • 13
    • 13
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GQLLQFESQV LATSCAAEAA SPSGPLRERG KTPATPTSQF VFSFPVSVGV
    预测反应
    Cow: 92%, Dog: 85%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 85%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against DUSP4. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product DUSP4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 394 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    别名
    DUSP4 (DUSP4 产品)
    别名
    zgc:55423 antibody, DUSP4 antibody, typ antibody, hvh2 antibody, mkp2 antibody, mkp-2 antibody, MGC131045 antibody, HVH2 antibody, MKP-2 antibody, MKP2 antibody, TYP antibody, 2700078F24Rik antibody, AI844617 antibody, BB104621 antibody, E130306H24Rik antibody, Mkp-2 antibody, Mkp2 antibody, dual specificity phosphatase 4 antibody, dual specificity phosphatase 4 S homeolog antibody, dusp4 antibody, DUSP4 antibody, dusp4.S antibody, Dusp4 antibody
    背景
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
    Alias Symbols: HVH2, MKP-2, MKP2, TYP
    Protein Interaction Partner: UBC, MAPK8, MAPK3, APP, CRMP1, GRIN1, MAPK9, GRIN2D, MAPK14, MAPK1,
    Protein Size: 394
    分子量
    43 kDa
    基因ID
    1846
    NCBI登录号
    NM_001394, NP_001385
    UniProt
    Q13115
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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