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DUSP4 抗体 (N-Term)

This anti-DUSP4 antibody is a 兔 多克隆 antibody detecting DUSP4 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 兔.
产品编号 ABIN2789727
发货至: 中国

Quick Overview for DUSP4 抗体 (N-Term) (ABIN2789727)

抗原

See all DUSP4 抗体
DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

适用

  • 57
  • 39
  • 8
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

  • 54
  • 4

克隆类型

  • 54
  • 4
多克隆

标记

  • 25
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This DUSP4 antibody is un-conjugated

应用范围

  • 44
  • 25
  • 22
  • 14
  • 13
  • 13
  • 9
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
    • 8
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    RAKGSVSLEQ ILPAEEEVRA RLRSGLYSAV IVYDERSPRA ESLREDSTVS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against DUSP4. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 394 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

    别名

    DUSP4

    背景

    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
    Alias Symbols: HVH2, MKP-2, MKP2, TYP
    Protein Interaction Partner: UBC, MAPK8, MAPK3, APP, CRMP1, GRIN1, MAPK9, GRIN2D, MAPK14, MAPK1,
    Protein Size: 394

    分子量

    43 kDa

    基因ID

    1846

    NCBI登录号

    NM_001394, NP_001385

    UniProt

    Q13115

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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