Melatonin Receptor 1B 抗体 (N-Term)
Quick Overview for Melatonin Receptor 1B 抗体 (N-Term) (ABIN2789720)
抗原
See all Melatonin Receptor 1B (MTNR1B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SFANCCEAGG WAVRPGWSGA GSARPSRTPR PPWVAPALSA VLIVTTAVDV
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预测反应
- Human: 100%, Pig: 79%, Rabbit: 79%
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产品特性
- This is a rabbit polyclonal antibody against MTNR1B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 362 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation." in: Carcinogenesis, Vol. 34, Issue 5, pp. 1051-61, (2013) (PubMed).
: "
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Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation." in: Carcinogenesis, Vol. 34, Issue 5, pp. 1051-61, (2013) (PubMed).
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- Melatonin Receptor 1B (MTNR1B)
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别名
- MTNR1B
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背景
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This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Alias Symbols: FGQTL2, MEL-1B-R, MT2
Protein Interaction Partner: GNAI1, GPR50, ITM2C, HNRNPA0, GNB4, PPM1G, PI4KA, PDIA6, VPS35, IRS4, COPA, CTNND1, MTNR1B, MTNR1A, FLNA, YWHAQ, GNB1, GNAI3, GNAI2, HSPA5, CANX,
Protein Size: 362 -
分子量
- 40 kDa
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基因ID
- 4544
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NCBI登录号
- NM_005959, NP_005950
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UniProt
- P49286
抗原
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