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Melatonin Receptor 1B 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-Melatonin Receptor 1B antibody specifically detects Melatonin Receptor 1B in WB. The antibody is reactive with 人, Pig 和 兔 samples.
产品编号 ABIN2789720
发货至: 中国
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Quick Overview for Melatonin Receptor 1B 抗体 (N-Term) (ABIN2789720)

抗原

See all Melatonin Receptor 1B (MTNR1B) 抗体
Melatonin Receptor 1B (MTNR1B)

适用

  • 30
  • 5
  • 2
  • 1
  • 1
人, Pig, 兔

宿主

  • 33
  • 1

克隆类型

  • 34
多克隆

标记

  • 22
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Melatonin Receptor 1B antibody is un-conjugated

应用范围

  • 17
  • 16
  • 10
  • 6
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    SFANCCEAGG WAVRPGWSGA GSARPSRTPR PPWVAPALSA VLIVTTAVDV

    预测反应

    Human: 100%, Pig: 79%, Rabbit: 79%

    产品特性

    This is a rabbit polyclonal antibody against MTNR1B. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 362 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Santoro, Mori, Marani, Grasso, Cambria, Blandino, Muti, Strano: "Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation." in: Carcinogenesis, Vol. 34, Issue 5, pp. 1051-61, (2013) (PubMed).

  • 抗原

    Melatonin Receptor 1B (MTNR1B)

    别名

    MTNR1B

    背景

    This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
    Alias Symbols: FGQTL2, MEL-1B-R, MT2
    Protein Interaction Partner: GNAI1, GPR50, ITM2C, HNRNPA0, GNB4, PPM1G, PI4KA, PDIA6, VPS35, IRS4, COPA, CTNND1, MTNR1B, MTNR1A, FLNA, YWHAQ, GNB1, GNAI3, GNAI2, HSPA5, CANX,
    Protein Size: 362

    分子量

    40 kDa

    基因ID

    4544

    NCBI登录号

    NM_005959, NP_005950

    UniProt

    P49286
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