SHANK2 抗体 (C-Term)
Quick Overview for SHANK2 抗体 (C-Term) (ABIN2789712)
抗原
See all SHANK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PQSPSLNSSQ PTNSADSKKP ASLSNCLPAS FLPPPESFDA VADSGIEEVD
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预测反应
- Cow: 100%, Dog: 85%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 85%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against SHANK2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1254 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))
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别名
- SHANK2
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背景
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This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain.
Alias Symbols: CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
Protein Interaction Partner: SHARPIN, NLK, LPHN1, DLGAP1, LPHN2, ARHGEF7, BAIAP2, DLG4, BAI2, DNM2, SSTR2, SLC9A3, CTTN, DLGAP3, DLGAP4, DLGAP2, DYNLL2, DYNLL1, MYO5A,
Protein Size: 1254 -
分子量
- 135 kDa
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基因ID
- 22941
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NCBI登录号
- NM_012309, NP_036441
抗原
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