Integrin Alpha2b 抗体 (N-Term)
Quick Overview for Integrin Alpha2b 抗体 (N-Term) (ABIN2789680)
抗原
See all Integrin Alpha2b (CD41) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - N-Term
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序列
 - QGLGASVVSW SDVIVACAPW QHWNVLEKTE EAEKTPVGSC FLAQPESGRR
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预测反应
 - Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 100%
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产品特性
 - This is a rabbit polyclonal antibody against ITGA2B. It was validated on Western Blot.
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纯化方法
 - Affinity Purified
 
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应用备注
 - Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1039 AA
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - Lot specific
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缓冲液
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze-thaw cycles.
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储存条件
 - -20 °C
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储存方法
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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- Integrin Alpha2b (CD41)
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别名
 - ITGA2B
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背景
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                        ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Alias Symbols: CD41, CD41B, GP2B, GPIIb, GTA, HPA3, GT, BDPLT2
Protein Interaction Partner: FBXO6, PRKACA, CAMK2A, ITGA2B, AUP1, CIB1, CLNS1A, VWF, TLN1, F2, CD36, ITGB3, FGA, COL1A2, COL2A1, CALR, GRB2, RNF181,
Protein Size: 1039 - 
                                            
分子量
 - 16 kDa
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基因ID
 - 3674
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NCBI登录号
 - NM_000419, NP_000410
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UniProt
 - P08514
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途径
 - Integrin Complex
 
抗原
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