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GIPR 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects GIPR in WB. It exhibits reactivity toward 人, 大鼠, Cow, 犬, 兔, 豚鼠, 马 和 Pig.
产品编号 ABIN2789673
发货至: 中国
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Quick Overview for GIPR 抗体 (N-Term) (ABIN2789673)

抗原

See all GIPR 抗体
GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

适用

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人, 大鼠, Cow, 犬, 兔, 豚鼠, 马, Pig

宿主

  • 63
  • 4
  • 1
兔

克隆类型

  • 61
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  • 2
多克隆

标记

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  • 4
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  • 1
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This GIPR antibody is un-conjugated

应用范围

  • 48
  • 18
  • 15
  • 7
  • 7
  • 7
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 10
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 1
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    N-Term

    原理

    GIPR Antibody - N-terminal region

    序列

    LRLSLCGLLL QRAETGSKGQ TAGELYQRWE RYRRECQETL AAAEPPSVAA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GIPR. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of human GIPR
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63934-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

    别名

    GIPR

    背景

    Background Information: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

    Gene Name: gastric inhibitory polypeptide receptor

    Alternative Symbols: PGQTL2

    Protein Name: gastric inhibitory polypeptide receptor

    分子量

    47kDa

    基因ID

    2696

    NCBI登录号

    NP_000155

    UniProt

    B7WP14

    途径

    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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