电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KIR2DS2 抗体 (N-Term)

KIR2DS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789655
发货至: 中国
  • 抗原 See all KIR2DS2 抗体
    KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
    抗原表位
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    N-Term
    适用
    宿主
    • 26
    克隆类型
    • 26
    多克隆
    标记
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    This KIR2DS2 antibody is un-conjugated
    应用范围
    • 21
    • 17
    • 16
    • 10
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    序列
    ETVILQCWSD VRFEHFLLHR EGKYKDTLHL IGEHHDGVSK ANFSIGPMMQ
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against KIR2DS2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product KIR2DS2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 304 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
    别名
    KIR2DS2 (KIR2DS2 产品)
    别名
    183ActI antibody, CD158J antibody, CD158b antibody, NKAT5 antibody, cl-49 antibody, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 antibody, KIR2DS2 antibody
    背景
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
    Alias Symbols: CU464060.1, 183ActI, CD158J, CD158b, NKAT5, cl-49
    Protein Interaction Partner: TYROBP, HLA-C, KIR2DS2,
    Protein Size: 304
    分子量
    32 kDa
    基因ID
    100132285
    NCBI登录号
    NM_012312, NP_036444
    UniProt
    D0UWM7
You are here:
客服