KIR2DS2 抗体 (N-Term)
Quick Overview for KIR2DS2 抗体 (N-Term) (ABIN2789655)
抗原
See all KIR2DS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ETVILQCWSD VRFEHFLLHR EGKYKDTLHL IGEHHDGVSK ANFSIGPMMQ
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against KIR2DS2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2) (AA 104-241) antibody
KIR2DS2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2) (AA 22-304) antibodyKIR2DS2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2) (AA 39-65) antibodyKIR2DS2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26424 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 304 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
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别名
- KIR2DS2
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背景
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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
Alias Symbols: CU464060.1, 183ActI, CD158J, CD158b, NKAT5, cl-49
Protein Interaction Partner: TYROBP, HLA-C, KIR2DS2,
Protein Size: 304 -
分子量
- 32 kDa
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基因ID
- 100132285
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NCBI登录号
- NM_012312, NP_036444
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UniProt
- D0UWM7
抗原
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