MCPH1 抗体 (C-Term)
Quick Overview for MCPH1 抗体 (C-Term) (ABIN2789647)
抗原
See all MCPH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VLDDSCDGFK DLIKPHEELK KSGRGKKPTR TLVMTSMPSE KQNVVIQVVD
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against MCPH1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 835 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MCPH1 (Microcephalin 1 (MCPH1))
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别名
- MCPH1
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背景
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This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome.
Alias Symbols: BRIT1, FLJ12847, MCT
Protein Interaction Partner: KDM1A, PHF11, TADA2A, ABCC2, E2F1, CDC27, CHD4, H2AFX, CHEK1, MDC1, TP53BP1, SMARCC2, SMARCC1, SMARCB1, SMARCA4, SMARCA2, RAD51, NBN, MCM2, BRCA2, ATR, ATM, RPA1,
Protein Size: 835 -
分子量
- 93 kDa
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基因ID
- 79648
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NCBI登录号
- NM_024596, NP_078872
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UniProt
- Q8NEM0
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途径
- Stem Cell Maintenance
抗原
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