SCG5 抗体 (C-Term)
Quick Overview for SCG5 抗体 (C-Term) (ABIN2789642)
抗原
See all SCG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QHLFDPEHDY PGLGKWNKKL LYEKMKGGER RKRRSVNPYL QGQRLDNVVA
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against SCG5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 212 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SCG5 (Secretogranin V (7B2 Protein) (SCG5))
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别名
- SCG5
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背景
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SCG5 acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. SCG5 binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. SCG5 is also required for cleavage of PCSK2 but does not appear to be involved in its folding. SCG5 plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
Alias Symbols: 7B2, P7B2, SGNE1, SgV
Protein Interaction Partner: UBQLN1, KHDRBS1, UBQLN4, NR1H2, PCSK2,
Protein Size: 212 -
分子量
- 23 kDa
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基因ID
- 6447
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NCBI登录号
- NM_001144757, NP_001138229
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UniProt
- P05408
抗原
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