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Transferrin Receptor 抗体 (N-Term)

This anti-Transferrin Receptor antibody is a 兔 多克隆 antibody detecting Transferrin Receptor in WB 和 IHC. Suitable for 人 和 兔.
产品编号 ABIN2789600
发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (N-Term) (ABIN2789600)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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人, 兔

宿主

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克隆类型

  • 200
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  • 4
多克隆

标记

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This Transferrin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 32
    • 16
    • 10
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    N-Term

    序列

    PVREEPGEDF PAARRLYWDD LKRKLSEKLD STDFTGTIKL LNENSYVPRE

    预测反应

    Human: 100%, Rabbit: 91%

    产品特性

    This is a rabbit polyclonal antibody against TFRC. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 760 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    TFRC

    背景

    TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
    Alias Symbols: CD71, TFR, TFR1, TRFR, T9, TR, p90
    Protein Interaction Partner: HUWE1, UBC, SGTA, CAV1, TP53, RAB8A, RANBP9, LGR4, MDM2, RPA3, RPA2, RPA1, ASB4, RNF2, OPTN, ADRB2, CLN3, MARCH8, env, MARCH1, MYO1G, VCAM1, ITGA4, FN1, ATF2, B4GALT1, ESR1, ATP6V1B1, FBXO6, KCNA5, KCNA3, vpu, SH3BP4, PARK2, LAPTM4B, LAPTM4A, HGS, SUMO2,
    Protein Size: 760

    分子量

    84 kDa

    基因ID

    7037

    NCBI登录号

    NM_003234, NP_003225

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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