MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. Alias Symbols: MAD1, PIG9, TP53I9, TXBP181 Protein Interaction Partner: CWF19L2, HAUS1, TSHZ3, CCDC94, ZSCAN32, CCHCR1, LGALSL, TRIM29, NEBL, USP15, SPATA2, BAG5, RNF8, TPM3, TPM1, PSMA1, MFAP1, TSC22D3, ALOX5, MAD2L1, TRIP13, UBC, TPR, CDC20, ZZEF1, FLNB, SIN3A, METTL21C, ZW10, MAD2L1BP, COIL, CDC27, NRD1, Cdk1, MNT, AMOTL2, Protein Size: 718