PDE6B 抗体 (C-Term)
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北京 101111
Quick Overview for PDE6B 抗体 (C-Term) (ABIN2789553)
抗原
See all PDE6B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PDE6B Antibody - C-terminal region
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序列
- RQHEHVIHLM DIAIIATDLA LYFKKRAMFQ KIVDESKNYQ DKKSWVEYLS
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against PDE6B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 25-237) antibody
PDE6B 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 1-190) antibodyPDE6B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 25-237) antibodyPDE6B 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC 宿主: 小鼠 Monoclonal 8I2F10 unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 25-237) antibodyPDE6B 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC 宿主: 小鼠 Monoclonal 8I2D7 unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) antibodyPDE6B 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (N-Term) antibodyPDE6B 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 105-154) antibodyPDE6B 适用: 人, Cow, 犬, 马, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 372-421) antibodyPDE6B 适用: 人, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 1-853) antibodyPDE6B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63580-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
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别名
- PDE6B
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背景
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Targeted Subunit: beta
Background Information: Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: Phosphodiesterase 6B, cGMP-specific, rod, beta
Alternative Symbols: rd1, PDEB, RP40, CSNB3, CSNBAD2, GMP-PDEbeta
Protein Name: Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
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分子量
- 98kDa
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基因ID
- 5158
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NCBI登录号
- NP_001138764
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UniProt
- E7ETT3
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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