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Macrophage Scavenger Receptor 1 抗体 (N-Term)

This anti-Macrophage Scavenger Receptor 1 antibody is a 兔 多克隆 antibody detecting Macrophage Scavenger Receptor 1 in WB. Suitable for 人, Pig, 犬, Cow 和 马.
产品编号 ABIN2789552
发货至: 中国

Quick Overview for Macrophage Scavenger Receptor 1 抗体 (N-Term) (ABIN2789552)

抗原

See all Macrophage Scavenger Receptor 1 (MSR1) 抗体
Macrophage Scavenger Receptor 1 (MSR1)

适用

  • 64
  • 60
  • 16
  • 16
  • 12
  • 11
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, Pig, 犬, Cow, 马

宿主

  • 60
  • 22
  • 6

克隆类型

  • 57
  • 26
  • 1
多克隆

标记

  • 41
  • 8
  • 7
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Macrophage Scavenger Receptor 1 antibody is un-conjugated

应用范围

  • 66
  • 41
  • 32
  • 19
  • 16
  • 14
  • 13
  • 13
  • 7
  • 7
  • 5
  • 5
  • 2
Western Blotting (WB)
  • 抗原表位

    • 16
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    VSSTNANDIT QSLTGKGNDS EEEMRFQEVF MEHMSNMEKR IQHILDMEAN

    预测反应

    Cow: 82%, Dog: 93%, Horse: 85%, Human: 100%, Pig: 82%

    产品特性

    This is a rabbit polyclonal antibody against MSR1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 451 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Macrophage Scavenger Receptor 1 (MSR1)

    别名

    MSR1

    背景

    This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
    Alias Symbols: CD204, SCARA1, SR-A, phSR1, phSR2, SRA
    Protein Interaction Partner: SEC22A, LEPROTL1, MALL, NKG7, ATP6V0C, IQCB1, TRAF6, HSPA1A,
    Protein Size: 451

    分子量

    50 kDa

    基因ID

    4481

    NCBI登录号

    NM_138715, NP_619729

    UniProt

    P21757
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