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Neural Wiskott-Aldrich syndrome protein (WASL) (Middle Region) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, Pig 和 兔.
产品编号 ABIN2789523
发货至: 中国

Quick Overview for Neural Wiskott-Aldrich syndrome protein (WASL) (Middle Region) 抗体 (ABIN2789523)

抗原

See all Neural Wiskott-Aldrich syndrome protein (WASL) 抗体
Neural Wiskott-Aldrich syndrome protein (WASL)

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔

宿主

  • 41
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克隆类型

  • 34
  • 12
多克隆

标记

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非结合性

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    ISHTKEKKKG KAKKKRLTKA DIGTPSNFQH IGHVGWDPNT GFDLNNLDPE

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against WASL. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 505 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Neural Wiskott-Aldrich syndrome protein (WASL)

    别名

    WASL

    背景

    The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.
    Alias Symbols: DKFZp779G0847, MGC48327, N-WASP, NWASP
    Protein Interaction Partner: RHOJ, ARPC3, RNF8, NCK2, WIPF1, SDCBP, PTK6, GRB2, IQGAP1, WWOX, SNX9, APBB1, PRPF40A, FNBP1L, FNBP1, TRIP10, PSTPIP1, ACTG1, SORBS3, ACTR2, ACTR3, LCK, CDC42, RPL7AP66, ZNF395, BAIAP2, ARPC1B, FCHSD2, IPO5, HP, HSP90AB1, HSP90AA1, SRC, WASF2, APP, WIPF2,
    Protein Size: 505

    分子量

    56 kDa

    基因ID

    8976

    NCBI登录号

    NM_003941, NP_003932

    UniProt

    O00401
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