CNR2 抗体 (C-Term)
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北京 101111
Quick Overview for CNR2 抗体 (C-Term) (ABIN2789519)
抗原
See all CNR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- CNR2 Antibody - C-terminal region
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序列
- MVNPVIYALR SGEIRSSAHH CLAHWKKCVR GLGSEAKEEA PRSSVTETEA
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预测反应
- Horse: 83%, Human: 100%, Mouse: 79%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against CNR2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63486-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13079-100, (2014) (PubMed).
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- CNR2 (Cannabinoid Receptor 2 (CNR2))
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别名
- CNR2
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背景
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Background Information: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Gene Name: Cannabinoid receptor 2 (macrophage)
Alternative Symbols: CB2, CX5, CB-2
Protein Name: Cannabinoid receptor 2
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分子量
- 40kDa
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基因ID
- 1269
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NCBI登录号
- NP_001832
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UniProt
- P34972
抗原
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