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SOCS2 抗体 (C-Term)

This 兔 多克隆 anti-SOCS2 antibody specifically detects SOCS2 in WB. The antibody is reactive with 人, 大鼠, 小鼠, Cow, Pig, 犬, 兔 和 豚鼠 samples.
产品编号 ABIN2789498
发货至: 中国
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Quick Overview for SOCS2 抗体 (C-Term) (ABIN2789498)

抗原

See all SOCS2 抗体
SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

适用

  • 53
  • 18
  • 9
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠, Cow, Pig, 犬, 兔, 豚鼠

宿主

  • 53
  • 3

克隆类型

  • 34
  • 22
多克隆

标记

  • 26
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This SOCS2 antibody is un-conjugated

应用范围

  • 29
  • 17
  • 14
  • 13
  • 12
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    KQFDSVVHLI DYYVQMCKDK RTGPEAPRNG TVHLYLTKPL YTSAPSLQHL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against SOCS2. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 198 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

    别名

    SOCS2

    背景

    This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.
    Alias Symbols: CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
    Protein Interaction Partner: Tceb1, CUL5, UBC, FLT3, ARFIP2, TPD52, PLA2G1B, BMI1, SOCS3, LCK, GHR, CCNC, RYBP, PTK2B, RNF7, TCEB2, EPOR, PTK2, PRLR, INSR, IGF1R, SOCS1,
    Protein Size: 198

    分子量

    22 kDa

    基因ID

    8835

    NCBI登录号

    NM_003877, NP_003868

    UniProt

    O14508

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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