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HAS1 抗体 (N-Term)

HAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789475
发货至: 中国
  • 抗原 See all HAS1 抗体
    HAS1 (Hyaluronan Synthase 1 (HAS1))
    抗原表位
    • 16
    • 8
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 49
    • 23
    • 22
    • 5
    • 5
    • 5
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠
    宿主
    • 44
    • 6
    克隆类型
    • 44
    • 6
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HAS1 antibody is un-conjugated
    应用范围
    • 26
    • 25
    • 20
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    序列
    EPAAAGAVGA GAYREVEAED PGRLAVEALV RTRRCVCVAQ RWGGKREVMY
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against HAS1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product HAS1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 578 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    HAS1 (Hyaluronan Synthase 1 (HAS1))
    别名
    HAS1 (HAS1 产品)
    别名
    dg42 antibody, Xhas1 antibody, HAS antibody, shas1 antibody, hyaluronan synthase 1 antibody, hyaluronan synthase 1 S homeolog antibody, has1 antibody, HAS1 antibody, Has1 antibody, has1.S antibody
    背景
    Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis.
    Alias Symbols: HAS
    Protein Interaction Partner: EWSR1, DDX1, VHL, EIF6,
    Protein Size: 578
    分子量
    64 kDa
    基因ID
    3036
    NCBI登录号
    NM_001523, NP_001514
    UniProt
    Q92839
    途径
    Glycosaminoglycan Metabolic Process
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