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HAS1 抗体 (N-Term)

This anti-HAS1 antibody is a 兔 多克隆 antibody detecting HAS1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬 和 豚鼠.
产品编号 ABIN2789475
发货至: 中国

Quick Overview for HAS1 抗体 (N-Term) (ABIN2789475)

抗原

See all HAS1 抗体
HAS1 (Hyaluronan Synthase 1 (HAS1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠

宿主

  • 47
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克隆类型

  • 47
  • 7
多克隆

标记

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This HAS1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    EPAAAGAVGA GAYREVEAED PGRLAVEALV RTRRCVCVAQ RWGGKREVMY

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against HAS1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 578 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HAS1 (Hyaluronan Synthase 1 (HAS1))

    别名

    HAS1

    背景

    Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis.
    Alias Symbols: HAS
    Protein Interaction Partner: EWSR1, DDX1, VHL, EIF6,
    Protein Size: 578

    分子量

    64 kDa

    基因ID

    3036

    NCBI登录号

    NM_001523, NP_001514

    UniProt

    Q92839

    途径

    Glycosaminoglycan Metabolic Process
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