Desmoglein 1 抗体 (C-Term)
Quick Overview for Desmoglein 1 抗体 (C-Term) (ABIN2789462)
抗原
See all Desmoglein 1 (DSG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GGIGLSSLGG TASIGHMRSS SDHHFNQTIG SASPSTARSR ITKYSTVQYS
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预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against DSG1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human DSG1
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anti-Desmoglein 1 (DSG1) (AA 30-90) antibody
DSG1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal 32-2B unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-544M unconjugated
anti-Desmoglein 1 (DSG1) (AA 384-539) antibodyDSG1 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 1-1049) antibodyDSG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 1-1049) antibodyDSG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (N-Term) antibodyDSG1 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 800-1049) antibodyDSG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 710-961) antibodyDSG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Desmoglein 1 (DSG1)
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别名
- DSG1
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背景
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This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
Alias Symbols: DG1, DSG, CDHF4, EPKHE, PPKS1, SPPK1, EPKHIA
Protein Size: 408 -
分子量
- 44 kDa
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基因ID
- 1828
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NCBI登录号
- NM_001942, NP_001933
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UniProt
- B7Z845
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途径
- Cell-Cell Junction Organization
抗原
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