VKORC1 抗体 (N-Term)
Quick Overview for VKORC1 抗体 (N-Term) (ABIN2789450)
抗原
See all VKORC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LHVKAARARD RDYRALCDVG TAISCSRVFS SRLPADTLGL CPDAAELPGV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against VKORC1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of VKORC1
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anti-Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) (AA 30-74) antibody
VKORC1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) (AA 27-76) antibodyVKORC1 适用: 人, Cow, 兔, Bat, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) (AA 15-41), (N-Term) antibodyVKORC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21964 unconjugated
anti-Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) (N-Term) antibodyVKORC1 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 92 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
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别名
- VKORC1
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背景
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Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.
Alias Symbols: EDTP308, FLJ00289, IMAGE3455200, MGC2694, MST134, MST576, VKCFD2, VKOR
Protein Interaction Partner: UBC, ILK, ZMYM6NB, TMEM242, SNORA12, TMEM256, ZCCHC24, METTL7B, SPTSSA, VKORC1L1, CCDC167, CCDC12, TMEM45B, KCNK17, JAGN1, SERP1, PPA2, TRAM1, TREX1, YIF1A, EBP, ARL6IP5, PROCR, IFITM3, ATP6AP2, BCAP31, PDIA6, HDAC6, HOMER2, VAPB, CLDN10, DPM2, REEP5, TF,
Protein Size: 92 -
分子量
- 10 kDa
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基因ID
- 79001
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NCBI登录号
- NM_206824, NP_996560
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UniProt
- Q9BQB6
抗原
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