TPMT 抗体 (C-Term)
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北京 101111
Quick Overview for TPMT 抗体 (C-Term) (ABIN2789428)
抗原
See all TPMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- TPMT Antibody - C-terminal region
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序列
- RGALVAINPG DRKCYADTMF SLLGKKFQYL LCVLSYDPTK HPGPPFYVPH
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预测反应
- Dog: 79%, Human: 100%, Pig: 79%
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产品特性
- This is a rabbit polyclonal antibody against TPMT. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63262-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TPMT (Thiopurine S-Methyltransferase (TPMT))
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别名
- TPMT
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背景
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Background Information: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Gene Name: Thiopurine S-methyltransferase
Alternative Symbols: TPMTD
Protein Name: Thiopurine S-methyltransferase
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分子量
- 27kDa
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基因ID
- 7172
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NCBI登录号
- NP_000358
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UniProt
- P51580
抗原
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