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TPMT 抗体 (C-Term)

This anti-TPMT antibody is a 兔 多克隆 antibody detecting TPMT in WB. Suitable for 人, 犬 和 Pig.
产品编号 ABIN2789428
发货至: 中国

Quick Overview for TPMT 抗体 (C-Term) (ABIN2789428)

抗原

See all TPMT 抗体
TPMT (Thiopurine S-Methyltransferase (TPMT))

适用

  • 46
  • 13
  • 13
  • 1
  • 1
人, 犬, Pig

宿主

  • 36
  • 10

克隆类型

  • 32
  • 14
多克隆

标记

  • 29
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TPMT antibody is un-conjugated

应用范围

  • 35
  • 21
  • 21
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    RGALVAINPG DRKCYADTMF SLLGKKFQYL LCVLSYDPTK HPGPPFYVPH

    预测反应

    Dog: 79%, Human: 100%, Pig: 79%

    产品特性

    This is a rabbit polyclonal antibody against TPMT. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 245 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TPMT (Thiopurine S-Methyltransferase (TPMT))

    别名

    TPMT

    背景

    This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
    Alias Symbols: -
    Protein Interaction Partner: APP, UBC,
    Protein Size: 245

    分子量

    27 kDa

    基因ID

    7172

    NCBI登录号

    NM_000367, NP_000358

    UniProt

    P51580
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