PIN1 抗体 (N-Term)
Quick Overview for PIN1 抗体 (N-Term) (ABIN2789425)
抗原
See all PIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RPSGNSSSGG KNGQGEPARV RCSHLLVKHS QSRRPSSWRQ EKITRTKEEA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against PIN1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 163 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
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别名
- PIN1
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背景
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Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: DOD, UBL5
Protein Interaction Partner: ANKRD40, KRTAP4-2, ZMIZ2, TSC22D4, THAP7, CCDC33, CEP76, HOMEZ, ZNF446, FBXW7, CEP55, ADAMTSL4, ZBTB7B, SSBP3, NUP62, MTUS2, ARHGEF15, IKZF3, RBPMS, RAI1, CCDC184, KRTAP10-3, KRTAP10-1, KRTAP10-9, KRTAP10-7, TAB3, ZBTB9, SPERT, AMOT, PRRC1, KRT40, HEXIM2,
Protein Size: 163 -
分子量
- 18 kDa
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基因ID
- 5300
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NCBI登录号
- NM_006221, NP_006212
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UniProt
- Q13526
抗原
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