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PDE5A 抗体 (C-Term)

This anti-PDE5A antibody is a 兔 多克隆 antibody detecting PDE5A in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2789423
发货至: 中国

Quick Overview for PDE5A 抗体 (C-Term) (ABIN2789423)

抗原

See all PDE5A 抗体
PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

适用

人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 23
  • 4
  • 1

克隆类型

  • 25
  • 3
多克隆

标记

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PDE5A antibody is un-conjugated

应用范围

  • 21
  • 13
  • 12
  • 11
  • 9
  • 7
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    C-Term

    序列

    TACDLSAITK PWPIQQRIAE LVATEFFDQG DRERKELNIE PTDLMNREKK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

    产品特性

    This is a rabbit polyclonal antibody against PDE5A. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 823 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ioki, Wu, Takayama, Motohashi, Wakai, Funahashi: "A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium." in: Theriogenology, Vol. 85, Issue 3, pp. 428-33, (2016) (PubMed).

  • 抗原

    PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

    别名

    PDE5A

    背景

    This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
    Alias Symbols: CGB-PDE, CN5A, PDE5, PDE5A1
    Protein Interaction Partner: UBC, PRKG1, CASP3,
    Protein Size: 823

    分子量

    93 kDa

    基因ID

    8654

    NCBI登录号

    NM_033437, NP_246273

    UniProt

    O76074

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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