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PRNP 抗体 (Middle Region)

Name: PRNP 抗体 (Middle Region)
SKU: ABIN2789398
Availability: OutOfStock

This anti-PRNP antibody is a 兔多克隆 antibody detecting PRNP in WB 和 IHC. Suitable for 人, 大鼠, Cow, 绵羊, 犬和山羊.

Western Blotting (WB) image for anti-Prion Protein (PRNP) (Middle Region) antibody (ABIN2789398) (PRNP 抗体 (Middle Region))

1 image

产品编号 ABIN2789398

发货至: 中国

Quick Overview for PRNP 抗体 (Middle Region) (ABIN2789398)

抗原

See all PRNP 抗体

PRNP (Prion Protein (PRNP))

适用

人, 大鼠, Cow, 绵羊, 犬, 山羊

宿主

兔

克隆类型

多克隆

标记

This PRNP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product PRNP Primary Antibody

抗原表位
15

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5

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2

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2

2

2

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1

1

1

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1

1

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1
Middle Region

序列

GGGTHNQWNK PSKPKTNLKH VAGAAAAGAV VGGLGGYMLG SAMSRPMIHF

预测反应

Cow: 100%, Dog: 100%, Goat: 100%, Human: 100%, Rat: 100%, Sheep: 100%

产品特性

This is a rabbit polyclonal antibody against Prnp. It was validated on Western Blot.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of Mouse Prnp
anti-Prion Protein (PRNP) (AA 23-230) antibody
PRNP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Prion Protein (PRNP) (AA 23-230) antibody
PRNP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G10G9 unconjugated

anti-Prion Protein (PRNP) antibody
PRNP 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prion Protein (PRNP) antibody
PRNP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Prion Protein (PRNP) (AA 23-230) antibody
PRNP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Prion Protein (PRNP) (AA 23-64) antibody
PRNP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Prion Protein (PRNP) antibody
PRNP 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prion Protein (PRNP) antibody
PRNP 适用: 人, Hamster WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal 3F4 unconjugated Recombinant Antibody

anti-Prion Protein (PRNP) (Prion) antibody
PRNP 适用: 人 WB 宿主: 小鼠 Monoclonal EM-20 unconjugated

anti-Prion Protein (PRNP) (AA 143-230) antibody
PRNP 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeat freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

PRNP (Prion Protein (PRNP))

别名

Prnp

背景

Prnp may play a role in neuronal development and synaptic plasticity, may be required for neuronal myelin sheath maintenance and may play a role in iron uptake and iron homeostasis. Prnp is a soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. It also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.
Alias Symbols: AA960666, AI325101, CD230, PrP, PrP, PrPC, PrPSc, Prn-i, Prn-p, Sinc, prP27-30, prP33-35C
Protein Interaction Partner: Dpp6, Eri3, Syn1, Grb2, Opcml, Lsamp, Ntm, Atp1a3, Igsf8, Cadm3, Clstn1, Pde10a, Adam23, Ywhaz, Ywhae, Stxbp1, Plp1, P4hb, Ncam2, Ncam1, Mog, Mbp, Mag, L1cam, Hspa5, Gnb1, Sparcl1, Dnm1, Dpysl2, Cntn1, Clu, Atp2b2, Atp1b1, Atp1a1, App, Apoe, Aplp2, Apbb1,
Protein Size: 254

分子量

28 kDa

基因ID

19122

NCBI登录号

NM_011170, NP_035300

UniProt

P04925

途径

Transition Metal Ion Homeostasis, Activated T Cell Proliferation