PRNP 抗体 (Middle Region)
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北京 101111
Quick Overview for PRNP 抗体 (Middle Region) (ABIN2789398)
抗原
See all PRNP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GGGTHNQWNK PSKPKTNLKH VAGAAAAGAV VGGLGGYMLG SAMSRPMIHF
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Human: 100%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against Prnp. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Prnp
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anti-Prion Protein (PRNP) (AA 23-230) antibody
PRNP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-230) antibodyPRNP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G10G9 unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-230) antibodyPRNP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-64) antibodyPRNP 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1945 unconjugated Recombinant Antibody
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, IHC, ELISA, IP, IHC (p) 宿主: 兔 Polyclonal T16-R unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal EM-20 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PRNP (Prion Protein (PRNP))
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别名
- Prnp
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背景
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Prnp may play a role in neuronal development and synaptic plasticity, may be required for neuronal myelin sheath maintenance and may play a role in iron uptake and iron homeostasis. Prnp is a soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. It also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.
Alias Symbols: AA960666, AI325101, CD230, PrP, PrP, PrPC, PrPSc, Prn-i, Prn-p, Sinc, prP27-30, prP33-35C
Protein Interaction Partner: Dpp6, Eri3, Syn1, Grb2, Opcml, Lsamp, Ntm, Atp1a3, Igsf8, Cadm3, Clstn1, Pde10a, Adam23, Ywhaz, Ywhae, Stxbp1, Plp1, P4hb, Ncam2, Ncam1, Mog, Mbp, Mag, L1cam, Hspa5, Gnb1, Sparcl1, Dnm1, Dpysl2, Cntn1, Clu, Atp2b2, Atp1b1, Atp1a1, App, Apoe, Aplp2, Apbb1,
Protein Size: 254 -
分子量
- 28 kDa
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基因ID
- 19122
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NCBI登录号
- NM_011170, NP_035300
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UniProt
- P04925
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途径
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
抗原
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