L1CAM 抗体 (C-Term)
Quick Overview for L1CAM 抗体 (C-Term) (ABIN2789372)
抗原
See all L1CAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GDIKPLGSDD SLADYGGSVD VQFNEDGSFI GQYSGKKEKE AAGGNDSSGA
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against L1CAM. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1257 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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别名
- L1CAM
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背景
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The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Alias Symbols: CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAML1, S10, SPG1, NCAM-L1, N-CAM-L1
Protein Interaction Partner: RANBP9, FBXO6, NRP1, Caskin1, RABGEF1, UBC, EZR, CANX, CNTN1, NUMB, PEA15, RPS6KA2, RPS6KA1, NCAN, MSN, ITGAV, CNTN2, ANK1, RDX, PRNP, ITGA5, NCAM1, CSNK2A1, ANK2, AP2A1, AP2M1,
Protein Size: 1257 -
分子量
- 138 kDa
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基因ID
- 3897
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NCBI登录号
- NM_000425, NP_000416
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UniProt
- P32004
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途径
- Synaptic Membrane
抗原
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