CD86 抗体 (C-Term)
Quick Overview for CD86 抗体 (C-Term) (ABIN2789334)
抗原
See all CD86 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- WKKKKRPRNS YKCGTNTMER EESEQTKKRE KIHIPERSDE AQRVFKSSKT
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预测反应
- Human: 100%, Pig: 92%
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产品特性
- This is a rabbit polyclonal antibody against CD86. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 217 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD86
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别名
- CD86
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背景
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This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Alias Symbols: B7-2, B70, CD28LG2, LAB72, MGC34413, B7.2
Protein Interaction Partner: UBC, CTLA4, ECE2, PARP1, MARCH1, MARCH8, CD86, CD28, CD80,
Protein Size: 217 -
分子量
- 23 kDa
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基因ID
- 942
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NCBI登录号
- NM_175862, NP_787058
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UniProt
- E9PC27
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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