FPGT 抗体 (C-Term)
Quick Overview for FPGT 抗体 (C-Term) (ABIN2789256)
抗原
See all FPGT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- TSLNVVVLNN SKFYHIGTTE EYLFYFTSDN SLKSELGLQS ITFSIFPDIP
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against FPGT. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human FPGT
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 594 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
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别名
- FPGT
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背景
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L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.
Alias Symbols: GFPP
Protein Interaction Partner: NLN,
Protein Size: 594 -
分子量
- 66 kDa
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基因ID
- 8790
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NCBI登录号
- NM_003838, NP_003829
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UniProt
- O14772
抗原
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