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CTPS2 抗体 (N-Term)

This anti-CTPS2 antibody is a 兔 多克隆 antibody detecting CTPS2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 兔, 斑马鱼 和 豚鼠.
产品编号 ABIN2789147
发货至: 中国

Quick Overview for CTPS2 抗体 (N-Term) (ABIN2789147)

抗原

See all CTPS2 抗体
CTPS2 (CTP Synthase II (CTPS2))

适用

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人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 兔, 斑马鱼, 豚鼠

宿主

  • 35

克隆类型

  • 35
多克隆

标记

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This CTPS2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    AKRENFCNIH VSLVPQLSAT GEQKTKPTQN SVRALRGLGL SPDLIVCRSS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against CTPS2. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 586 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CTPS2 (CTP Synthase II (CTPS2))

    别名

    CTPS2

    背景

    The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
    Alias Symbols: DKFZp686C17207, FLJ43358, MGC32997
    Protein Interaction Partner: CTPS2, SPG21, RNF2, LRSAM1, EHD4, EHD1, PLIN3, MTMR2, WARS, PRKDC, NUCB1, METTL1, KTN1, HSF1, GTF2I, DHPS, RPL37A, RPL23A, FGFR1, CTBP2, UBC, SUMO2, OTUD5,
    Protein Size: 586

    分子量

    64 kDa

    基因ID

    56474

    NCBI登录号

    NM_175859, NP_787055

    UniProt

    Q9NRF8

    途径

    Ribonucleoside Biosynthetic Process
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