CTPS2 抗体 (N-Term)
Quick Overview for CTPS2 抗体 (N-Term) (ABIN2789147)
抗原
See all CTPS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AKRENFCNIH VSLVPQLSAT GEQKTKPTQN SVRALRGLGL SPDLIVCRSS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CTPS2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 586 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CTPS2 (CTP Synthase II (CTPS2))
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别名
- CTPS2
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背景
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The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
Alias Symbols: DKFZp686C17207, FLJ43358, MGC32997
Protein Interaction Partner: CTPS2, SPG21, RNF2, LRSAM1, EHD4, EHD1, PLIN3, MTMR2, WARS, PRKDC, NUCB1, METTL1, KTN1, HSF1, GTF2I, DHPS, RPL37A, RPL23A, FGFR1, CTBP2, UBC, SUMO2, OTUD5,
Protein Size: 586 -
分子量
- 64 kDa
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基因ID
- 56474
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NCBI登录号
- NM_175859, NP_787055
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UniProt
- Q9NRF8
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途径
- Ribonucleoside Biosynthetic Process
抗原
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