BRE 抗体 (C-Term)
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北京 101111
Quick Overview for BRE 抗体 (C-Term) (ABIN2789082)
抗原
See all BRE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- BABAM2 Antibody - C-terminal region
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序列
- YHFTNSGQLY SQAQKNYPYS PRWDGNEMAK RAKAYFKTFV PQFQEAAFAN
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against BRE. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62254-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
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别名
- BABAM2
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背景
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Targeted Subunit: BRE
Background Information: This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
Gene Name: BRISC and BRCA1 A complex member 2
Alternative Symbols: BRE, BRCC4, BRCC45
Protein Name: BRISC and BRCA1-A complex member 2
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分子量
- 43kDa
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基因ID
- 9577
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NCBI登录号
- NP_954664
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UniProt
- Q9NXR7
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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