GPER 抗体 (C-Term)
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- 抗原 See all GPER 抗体
- GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPER antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SFLGETFRDK LRLYIEQKTN LPALNRFCHA ALKAVIPDST EQSDVRFSSA
- 预测反应
- Dog: 100%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against GPER. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product GPER Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 375 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))
- 别名
- GPER (GPER 产品)
- 背景
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This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Alias Symbols: CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPR30, LERGU, LERGU2, LyGPR, MGC99678, GPER
Protein Interaction Partner: UBC,
Protein Size: 375 - 分子量
- 42 kDa
- 基因ID
- 2852
- NCBI登录号
- NM_001098201, NP_001091671
- UniProt
- Q99527
- 途径
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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