HRH3 抗体 (N-Term)
Quick Overview for HRH3 抗体 (N-Term) (ABIN2789052)
抗原
See all HRH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VFNIVLISYD RFLSVTRAVS YRAQQGDTRR AVRKMALVWV LAFLLYGPAI
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Hrh3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Hrh3
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 445 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HRH3 (Histamine Receptor H3 (HRH3))
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别名
- Hrh3
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背景
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This gene encodes a histamine H3 receptor that belongs to the superfamily of G-protein coupled receptors. This protein functions as a presynaptic autoreceptor on histamine neurons in the brain, and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. It is deemed a great target for the development of therapeutics for numerous disorders, including obesity, epilepsy, and such cognitive diseases as attention deficit hyperactivity disorder and Alzheimer's disease. Several alternatively spliced transcript variants encoding different isoforms, with different brain expression patterns and signaling properties, have been described for this gene.
Alias Symbols: -
Protein Size: 445 -
分子量
- 48 kDa
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基因ID
- 85268
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NCBI登录号
- NM_053506, NP_445958
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UniProt
- Q9QYN8
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途径
- cAMP Metabolic Process, Feeding Behaviour
抗原
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