CDK14 抗体 (C-Term)
Quick Overview for CDK14 抗体 (C-Term) (ABIN2788962)
抗原
See all CDK14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SDLPPRLWEL TDMSSIFTVP NVRLQPEAGE SMRAFGKNNS YGKSLSNSKH
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预测反应
- Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Cdk14. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Cyclin-Dependent Kinase 14 (CDK14) (AA 67-96), (N-Term) antibody
CDK14 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18842 unconjugated
anti-Cyclin-Dependent Kinase 14 (CDK14) (AA 1-30), (N-Term) antibodyCDK14 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3365-3366 unconjugated
anti-Cyclin-Dependent Kinase 14 (CDK14) (AA 1-451) antibodyCDK14 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 14 (CDK14) antibodyCDK14 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 14 (CDK14) (AA 1-100) antibodyCDK14 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 14 (CDK14) (AA 312-451) antibodyCDK14 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 469 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDK14 (Cyclin-Dependent Kinase 14 (CDK14))
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别名
- Cdk14
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背景
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Cdk14 is a Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Cdk14 acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Cdk14 acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. Cdk14 may also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Alias Symbols: Pftk1, mKIAA0834
Protein Interaction Partner: SMURF1, TGFBR1, BMPR1B, ACVR1,
Protein Size: 469 -
分子量
- 53 kDa
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基因ID
- 18647
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NCBI登录号
- NM_011074, NP_035204
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UniProt
- O35495
抗原
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