CDK14 抗体 (C-Term)
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- 抗原 See all CDK14 抗体
- CDK14 (Cyclin-Dependent Kinase 14 (CDK14))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, 犬, Pig, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK14 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SDLPPRLWEL TDMSSIFTVP NVRLQPEAGE SMRAFGKNNS YGKSLSNSKH
- 预测反应
- Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Cdk14. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product CDK14 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 469 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CDK14 (Cyclin-Dependent Kinase 14 (CDK14))
- 别名
- Cdk14 (CDK14 产品)
- 背景
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Cdk14 is a Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Cdk14 acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Cdk14 acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. Cdk14 may also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Alias Symbols: Pftk1, mKIAA0834
Protein Interaction Partner: SMURF1, TGFBR1, BMPR1B, ACVR1,
Protein Size: 469 - 分子量
- 53 kDa
- 基因ID
- 18647
- NCBI登录号
- NM_011074, NP_035204
- UniProt
- O35495
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