PFKFB1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for PFKFB1 抗体 (C-Term) (ABIN2788933)
抗原
See all PFKFB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- PFKFB1 Antibody - C-terminal region
-
序列
- CPLHTVLKLT PVAYGCKVES IYLNVEAVNT HREKPENVDI TREPEEALDT
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
-
产品特性
- This is a rabbit polyclonal antibody against PFKFB1. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61878-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
-
别名
- PFKFB1
-
背景
-
Background Information: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Alternative Symbols: F6PK, HL2K, PFRX
Protein Name: 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1 EMBL AAH96078.1
-
分子量
- 52kDa
-
基因ID
- 5207
-
NCBI登录号
- NP_002616
-
UniProt
- Q4VBA8
-
途径
- Regulation of Carbohydrate Metabolic Process
抗原
-