CDK11 抗体 (Middle Region)
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北京 101111
Quick Overview for CDK11 抗体 (Middle Region) (ABIN2788891)
抗原
See all CDK11 (CDK11B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- CDK11B Antibody - middle region
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序列
- REQEKELREQ EKELREQKEL REQEEQMQEQ EEKMWEQEEK MREQEEKMWR
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 90%
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产品特性
- This is a rabbit polyclonal antibody against LOC283685. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CDK11B
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61760-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))
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别名
- CDK11B
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背景
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Background Information: This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.
Gene Name: cyclin-dependent kinase 11B
Alternative Symbols: p58, PK58, CDK11, CLK-1, CDC2L1, PITSLREA, p58CLK-1, CDK11-p46, CDK11-p58, p58CDC2L1, CDK11-p110
Protein Name: cyclin-dependent kinase 11B
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分子量
- 34kDa
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基因ID
- 984
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NCBI登录号
- NP_277022
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UniProt
- P21127
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途径
- Regulation of Lipid Metabolism by PPARalpha, M Phase
抗原
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