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GIT2 抗体 (C-Term)

This anti-GIT2 antibody is a 兔 多克隆 antibody detecting GIT2 in WB. Suitable for 人, 大鼠, 犬, Cow, 马, Pig, 豚鼠 和 兔.
产品编号 ABIN2788863
发货至: 中国

Quick Overview for GIT2 抗体 (C-Term) (ABIN2788863)

抗原

See all GIT2 抗体
GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

适用

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  • 15
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人, 大鼠, 犬, Cow, 马, Pig, 豚鼠, 兔

宿主

  • 36
  • 14

克隆类型

  • 38
  • 12
多克隆

标记

  • 35
  • 2
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  • 1
  • 1
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This GIT2 antibody is un-conjugated

应用范围

  • 32
  • 17
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  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
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    • 3
    • 2
    • 1
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    • 1
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    • 1
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    • 1
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    C-Term

    序列

    VQTGSEYTDT SNHSSLKRRP SARGSRPMSM YETGSGQKPY LPMGEASRPE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against GIT2. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 759 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

    别名

    GIT2

    背景

    This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined.
    Alias Symbols: CAT-2, DKFZp686G01261, KIAA0148, MGC760, CAT2
    Protein Interaction Partner: UBC, QPRT, ATF5, CORO1A, HNRNPUL1, TNIP1, CALCOCO2, MVP, RUSC2, SAFB2, IKBKG, SPOP, TSN, TRAF1, TNFAIP3, RCVRN, PROX1, NME2, NFKBIB, SMAD3, LMNB1, KRT18, HGD, GUSB, GCH1, E2F2, C4BPA, ACTN1, ACTG1, Dlg4, POLR1B, USHBP1, RUFY1, SH3GLB2, KCTD5, UBQLN1, EDC4
    Protein Size: 759

    分子量

    83 kDa

    基因ID

    9815

    NCBI登录号

    NM_057169, NP_476510

    UniProt

    Q14161

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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