PEX19 抗体 (C-Term)
Quick Overview for PEX19 抗体 (C-Term) (ABIN2788834)
抗原
See all PEX19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- AETPTDSETT QKARFEMVLD LMQQLQDLGH PPKELAGEMP PGLNFDLDAL
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against PEX19. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 299 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))
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别名
- PEX19
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背景
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This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Alias Symbols: D1S2223E, FLJ55296, HK33, PMP1, PMPI, PXF, PXMP1
Protein Interaction Partner: FKBP7, IL23A, PEX3, UBC, PPIB, PTPLAD1, VCP, PXMP4, SLC25A17, PEX16, PEX11B, ABCD3, PMP22, EGFR, Cdkn2a, Pxmp2, TMEM54, MFSD5, PEX26, GSKIP, F11R, KIFAP3, OIP5, EIF1B, PEX11A, STK3, SRPK1, PEX14, PEX13, SMAD2, IRF3, CDC25A, NUDCD2, DSTN, NUBP2, HSPB1, PEX
Protein Size: 299 -
分子量
- 33 kDa
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基因ID
- 5824
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NCBI登录号
- NM_002857, NP_002848
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UniProt
- P40855
抗原
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