PDLIM7 抗体 (N-Term)
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Quick Overview for PDLIM7 抗体 (N-Term) (ABIN2788823)
抗原
See all PDLIM7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RLMENTEDWR PRPGTGQSRS FRILAHLTGT EFMQDPDEEH LKKSSQVPRT
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against PDLIM7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of HUMAN PDLIM7
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))
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别名
- PDLIM7
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背景
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The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Protein Interaction Partner: WWP2, IQGAP1, TSG101, PHF1, DGCR6, BAG3, RET, CBLC, COPS5, PARP1, YAP1, HNRNPD, PRKD2, ZMYND11, TRADD, UBC, SH3BP2, MYC, Hoxa1, NDUFA7, PCBP1, UBQLN4, TRAF3, TRAF2, TAB2, TRAF6, NR2C2, SMURF1, TP53, MDM2, Cdk1, PSMF1, SH2B2, C20orf195, AP5B1, ENKD1, TPM2,
Protein Size: 287 -
分子量
- 31 kDa
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基因ID
- 9260
抗原
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