RPS6 抗体 (C-Term)
Quick Overview for RPS6 抗体 (C-Term) (ABIN2788795)
抗原
See all RPS6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- KKNKEEAAEY AKLLAKRMKE AKEKRQEQIA KRRRLSSLRA STSKSESSQK
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against RPS6. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 249 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RPS6 (Ribosomal Protein S6 (RPS6))
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别名
- RPS6
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背景
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: S6
Protein Interaction Partner: MDM2, CEP250, TUBGCP3, VCP, TUBG1, TP53, SUMO2, UIMC1, STAU1, UBC, rev, HNRNPU, FAU, EIF3CL, WIBG, WDR26, PNO1, RPS29, RPS28, RPS27, RPS26, RPS25, RPS24, RPS23, RPS20, RPS19, RPS18, RPS16, RPS15A, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS5, RPS4X,
Protein Size: 249 -
分子量
- 27 kDa
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基因ID
- 6194
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NCBI登录号
- NM_001010, NP_001001
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UniProt
- P62753
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途径
- Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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