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GALR2 抗体 (C-Term)

GALR2 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788788
发货至: 中国
  • 抗原 See all GALR2 抗体
    GALR2 (Galanin Receptor 2 (GALR2))
    抗原表位
    • 16
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    • 1
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    C-Term
    适用
    • 38
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    人, 马
    宿主
    • 38
    • 1
    克隆类型
    • 39
    多克隆
    标记
    • 17
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    This GALR2 antibody is un-conjugated
    应用范围
    • 33
    • 18
    • 13
    • 13
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    序列
    RGTHSGSVLE RESSDLLHMS EAAGALRPCP GASQPCILEP CPGPSWQGPK
    预测反应
    Horse: 93%, Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against GALR2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product GALR2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 387 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    GALR2 (Galanin Receptor 2 (GALR2))
    别名
    GALR2 (GALR2 产品)
    别名
    GALNR2 antibody, mGalR antibody, GALR2 antibody, GAL2-R antibody, GALR-2 antibody, galanin receptor 2 antibody, transcription regulator. LacI family, raffinose related antibody, DNA-binding transcriptional regulator GalR antibody, galactose operon repressor antibody, galanin receptor type 2 antibody, GALR2 antibody, Galr2 antibody, LOC100037698 antibody, rafR antibody, galR2 antibody, LOC103690156 antibody
    背景
    Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
    Alias Symbols: GALNR2, MGC125983, MGC125984
    Protein Interaction Partner: GNAQ, GAL,
    Protein Size: 387
    分子量
    43 kDa
    基因ID
    8811
    NCBI登录号
    NM_003857, NP_003848
    UniProt
    O43603
    途径
    cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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