GALR2 抗体 (C-Term)
Quick Overview for GALR2 抗体 (C-Term) (ABIN2788788)
抗原
See all GALR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RGTHSGSVLE RESSDLLHMS EAAGALRPCP GASQPCILEP CPGPSWQGPK
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预测反应
- Horse: 93%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against GALR2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Galanin Receptor 2 (GALR2) (AA 51-150) antibody
GALR2 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Transmembrane Domain) antibodyGALR2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (C-Term) antibodyGALR2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 282-387) antibodyGALR2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) antibodyGALR2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Internal Region) antibodyVerified GALR2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 50-150) antibodyGALR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 223-235) antibodyGALR2 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 387 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GALR2 (Galanin Receptor 2 (GALR2))
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别名
- GALR2
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背景
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Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
Alias Symbols: GALNR2, MGC125983, MGC125984
Protein Interaction Partner: GNAQ, GAL,
Protein Size: 387 -
分子量
- 43 kDa
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基因ID
- 8811
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NCBI登录号
- NM_003857, NP_003848
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UniProt
- O43603
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途径
- cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
抗原
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