HARS1/Jo-1 抗体 (N-Term)
Quick Overview for HARS1/Jo-1 抗体 (N-Term) (ABIN2788770)
抗原
See all HARS1/Jo-1 (HARS1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FVLKTPKGTR DYSPRQMAVR EKVFDVIIRC FKRHGAEVID TPVFELKETL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against HARS. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HARS
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 509 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
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别名
- HARS
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背景
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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Alias Symbols: FLJ20491, HRS, USH3B
Protein Interaction Partner: UBC, AARSD1, ACBD3, ELAC2, XPO5, THG1L, NSUN2, RPUSD2, SNF8, IPO7, EFTUD2, TTC1, SHMT1, PFDN1, GTF2E1, FEN1, CALU, PI4KA, G6PD, EIF2D, ANXA5, UBD, SUMO1, TNIK, STAM, EIF3I, EEF1G, RPL5, EEF1B2, TARS,
Protein Size: 509 -
分子量
- 56 kDa
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基因ID
- 3035
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NCBI登录号
- NM_002109, NP_002100
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UniProt
- P12081
抗原
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