HARS1/Jo-1 抗体 (N-Term)
-
- 抗原 See all HARS1/Jo-1 (HARS1) 抗体
- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HARS1/Jo-1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- FVLKTPKGTR DYSPRQMAVR EKVFDVIIRC FKRHGAEVID TPVFELKETL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against HARS. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HARS
- Top Product
- Discover our top product HARS1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 509 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
- 别名
- HARS (HARS1 产品)
- 背景
-
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Alias Symbols: FLJ20491, HRS, USH3B
Protein Interaction Partner: UBC, AARSD1, ACBD3, ELAC2, XPO5, THG1L, NSUN2, RPUSD2, SNF8, IPO7, EFTUD2, TTC1, SHMT1, PFDN1, GTF2E1, FEN1, CALU, PI4KA, G6PD, EIF2D, ANXA5, UBD, SUMO1, TNIK, STAM, EIF3I, EEF1G, RPL5, EEF1B2, TARS,
Protein Size: 509 - 分子量
- 56 kDa
- 基因ID
- 3035
- NCBI登录号
- NM_002109, NP_002100
- UniProt
- P12081
-