RCC1 抗体 (C-Term)
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- 抗原 See all RCC1 抗体
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RCC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AWGMGTNYQL GTGQDEDAWS PVEMMGKQLE NRVVLSVSSG GQHTVLLVKD
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RCC1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product RCC1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 421 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
- 别名
- RCC1 (RCC1 产品)
- 别名
- Chc1 antibody, zgc:65796 antibody, zgc:77114 antibody, wu:fj77f08 antibody, rcc1 antibody, chc1-a antibody, BJ1 antibody, CG10480 antibody, CG18640 (Bj1) antibody, Dmel\\CG10480 antibody, RCC1 antibody, RanGEF antibody, Rcc1 antibody, dRCC1 antibody, inxs antibody, sdt antibody, xrcc1 antibody, chc1-b antibody, MGC115703 antibody, MGC132085 antibody, CHC1 antibody, RCC1-I antibody, SNHG3-RCC1 antibody, 4931417M11Rik antibody, AI326872 antibody, regulator of chromosome condensation 1 antibody, regulator of chromosome condensation 1 L homeolog antibody, Regulator of chromosome condensation 1 antibody, N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted antibody, regulator of chromosome condensation 1 S homeolog antibody, rcc1 antibody, RCC1 antibody, rcc1.L antibody, Rcc1 antibody, rcc1.S antibody
- 背景
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RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Alias Symbols: CHC1, RCC1-I, SNHG3-RCC1
Protein Interaction Partner: UBC, SUMO2, SUMO1, NEDD8, MDM2, SUZ12, RNF2, PTMA, HDAC9, HMGA1, VCAM1, ITGA4, FN1, U2AF1, RANBP1, RAN, HNRNPM, HNRNPK, LUC7L3, SF3B6, NCSTN, ACIN1, RBM14, HDGF, SPRED1, FLAD1, WIZ, LRIF1, CSAD, SDF4, TRMT2A, DDAH2, FAF1, NUDT21, CCT7, TUBB3, CDK2AP2, KMT
Protein Size: 421 - 分子量
- 45 kDa
- 基因ID
- 1104
- NCBI登录号
- NM_001269, NP_001260
- UniProt
- P18754
- 途径
- Chromatin Binding, Protein targeting to Nucleus
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