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RCC1 抗体 (C-Term)

This anti-RCC1 antibody is a 兔 多克隆 antibody detecting RCC1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼.
产品编号 ABIN2788760
发货至: 中国

Quick Overview for RCC1 抗体 (C-Term) (ABIN2788760)

抗原

See all RCC1 抗体
RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This RCC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    AWGMGTNYQL GTGQDEDAWS PVEMMGKQLE NRVVLSVSSG GQHTVLLVKD

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against RCC1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 421 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

    别名

    RCC1

    背景

    RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
    Alias Symbols: CHC1, RCC1-I, SNHG3-RCC1
    Protein Interaction Partner: UBC, SUMO2, SUMO1, NEDD8, MDM2, SUZ12, RNF2, PTMA, HDAC9, HMGA1, VCAM1, ITGA4, FN1, U2AF1, RANBP1, RAN, HNRNPM, HNRNPK, LUC7L3, SF3B6, NCSTN, ACIN1, RBM14, HDGF, SPRED1, FLAD1, WIZ, LRIF1, CSAD, SDF4, TRMT2A, DDAH2, FAF1, NUDT21, CCT7, TUBB3, CDK2AP2, KMT
    Protein Size: 421

    分子量

    45 kDa

    基因ID

    1104

    NCBI登录号

    NM_001269, NP_001260

    UniProt

    P18754

    途径

    Chromatin Binding, Protein targeting to Nucleus
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