UGDH 抗体 (C-Term)
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Quick Overview for UGDH 抗体 (C-Term) (ABIN2788735)
抗原
See all UGDH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VLDGLHNELQ TIGFQIETIG KKVSSKRIPY APSGEIPKFS LQDPPNKKPK
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预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against UGDH. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 494 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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别名
- UGDH
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背景
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The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
Alias Symbols: GDH, UDP-GlcDH, UDPGDH, UGD
Protein Interaction Partner: UGDH, CIAO1, SUMO2, UBC, XPO5, MAT2B, RPUSD2, GORASP2, BOP1, RNASEH2A, ATG7, PDIA6, SNX1, PRKACA, ME1, MAT2A, GTF2A1, GARS, CTTN, BAG3, UGT1A1, RAD51, UBE2V1, TKT, ELAVL1, SIRT1, SIRT3, TERF2, AK5,
Protein Size: 494 -
分子量
- 54 kDa
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基因ID
- 7358
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NCBI登录号
- NM_003359, NP_003350
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UniProt
- O60701
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途径
- Glycosaminoglycan Metabolic Process
抗原
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